化工社化工社 化学情報印刷レポート · 研究参考用
3-(3-cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester → 3-(7-Fluoro-1H-indol-5-yl)-N-Methyl-3-phenyl-acrylamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(3-cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester | HCID 67355322 | — |
| 反応物 | 3-(7-fluoro-1H-indol-5-yl)-3-phenyl-acrylic acid ethyl ester | HCID 67355655 | — |
| 生成物 | 3-(7-Fluoro-1H-indol-5-yl)-N-Methyl-3-phenyl-acrylamide | HCID 67355386 | 59% |
反応手順
3-(7-Fluoro-1H-indol-5-yl)-N-Methyl-3-phenyl-acrylamide LXXXII (120 mg, 59% yield) was prepared from 3-(7-fluoro-1H-indol-5-yl)-3-phenyl-acrylic acid ethyl ester using the procedure described above for 3-(1H-Indol-7-yl)-N-methyl-3-phenyl-acrylamide XVIII (see Example 4).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07446118B2 |
| 出典データセット | uspto-grants-2008_11 |
| ORD ID | ord-467e033397e34911ab25070adf40f76b |
| 出典メモ | uspto-grants-2008_11 |