HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-bromo-7-methoxy-1H-indole → 3-(7-Methoxy-1H-indol-5-yl)-3-phenyl-acrylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-bromo-7-methoxy-1H-indole | HCID 19804063 | — |
| Reactant | 3-(7-Methoxy-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester | HCID 67356083 | — |
| Product | 3-(7-Methoxy-1H-indol-5-yl)-3-phenyl-acrylic acid ethyl ester | HCID 67355733 | 50% |
Reaction Steps
3-(7-Methoxy-1H-indol-5-yl)-3-phenyl-acrylic acid ethyl ester CVI (120 mg, 50% yield) was prepared from 5-bromo-7-methoxyindole using the procedure described above for preparation of 3-(7-Methoxy-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester LIII (Example 13).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446118B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-6bc2b0983c2c4cddac60bdbfa500bf75 |
| Source note | uspto-grants-2008_11 |