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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268822Generated: November 2, 2026

6-Bromo-5-methoxy-1H-indole → 3-(5-Methoxy-1H-indol-6-yl)-3-phenyl-acrylic acid ethyl ester

https://huagongshe.com/reaction/268822

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Bromo-5-methoxy-1H-indoleHCID 14546585—
Reactant3-(5-Methoxy-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl esterHCID 67355784—
Product3-(5-Methoxy-1H-indol-6-yl)-3-phenyl-acrylic acid ethyl esterHCID 67356690—

Reaction Steps

3-(5-Methoxy-1H-indol-6-yl)-3-phenyl-acrylic acid ethyl ester CXXXIII was prepared from 6-bromo-5-methoxyindole XLVII uisng the procedure described above for preparation of 3-(5-Methoxy-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester XLVIII (Example 12).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446118B2
Source datasetuspto-grants-2008_11
ORD IDord-bb1ba32671bd4d4787d14c930f453060
Source noteuspto-grants-2008_11