3-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamide → 3-(7-Methoxy-1H-indol-6-yl)-N-methyl-3-phenyl-propionamide

HRID 268827Notes

Reaction equation

HRID 268827 reaction equation
[CH3:1][O:2][C:3]1[C:4]([C:12]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:13][C:14]([NH:16][CH3:17])=[O:15])=[CH:5][CH:6]=[C:7]2[C:11]=1[NH:10][CH:9]=[CH:8]2.N1C2C(=CC=CC=2C(C2C=CC=CC=2)CC(NC)=O)C=C1>>[CH3:1][O:2][C:3]1[C:4]([CH:12]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH2:13][C:14]([NH:16][CH3:17])=[O:15])=[CH:5][CH:6]=[C:7]2[C:11]=1[NH:10][CH:9]=[CH:8]2

Participants

3

Reactant 2

HCID 598317453-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamideHCID 673550943-(7-methoxy-1H-indol-6-yl)-N-methyl-3-phenyl-acrylamide

Product 1

HCID 673565093-(7-Methoxy-1H-indol-6-yl)-N-methyl-3-phenyl-propionamide

Procedure

3-(7-Methoxy-1H-indol-6-yl)-N-methyl-3-phenyl-propionamide CXL was prepared from 3-(7-methoxy-1H-indol-6-yl)-N-methyl-3-phenyl-acrylamide using the procedure described above for preparation of 3-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamide XIX (Example 4).

Sources & evidence

ORD record
ord-865f55cc396f428889f11b7f0502c1de
Source dataset
uspto-grants-2008_11
Patent number
US07446118B2

Reaction notes

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