[3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amine → Methyl-[3-(1-methyl-1H-indol-6-yl)-3-phenyl-propyl]-amine

HRID 268832Notes

Reaction equation

HRID 268832 reaction equation
[CH3:1][NH:2][C:3](=O)[CH2:4][CH:5]([C:12]1[CH:20]=[C:19]2[C:15]([CH:16]=[CH:17][N:18]2[CH3:21])=[CH:14][CH:13]=1)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.N1C2C(=CC=CC=2C(C2C=CC=CC=2)CCNC)C=C1>>[CH3:1][NH:2][CH2:3][CH2:4][CH:5]([C:12]1[CH:20]=[C:19]2[C:15]([CH:16]=[CH:17][N:18]2[CH3:21])=[CH:14][CH:13]=1)[C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1

Participants

3

Reactant 2

HCID 17747555[3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amineHCID 59831892N-Methyl-3-(1-methyl-1H-indol-6-yl)-3-phenyl-propionamide

Product 1

HCID 59831662Methyl-[3-(1-methyl-1H-indol-6-yl)-3-phenyl-propyl]-amine

Procedure

Methyl-[3-(1-methyl-1H-indol-6-yl)-3-phenyl-propyl]-amine CXLVI was prepared as a hydrochloride salt from N-methyl-3-(1-methyl-1H-indol-6-yl)-3-phenyl-propionamide using the procedure described above for preparation of [3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amine XX (Example 4). MS (M+H)=279.

Sources & evidence

ORD record
ord-e1a287ccfd3e4f1194d3f617552eb690
Source dataset
uspto-grants-2008_11
Patent number
US07446118B2

Reaction notes

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