HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromo-1H-indole-3-carbonitrile → 3-(3-Cyano-1H-indol-6-yl)-3-phenyl-acrylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromo-1H-indole-3-carbonitrile | HCID 11470067 | — |
| Reactant | 3-(6-Methoxy-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester | HCID 67356090 | — |
| Product | 3-(3-Cyano-1H-indol-6-yl)-3-phenyl-acrylic acid ethyl ester | HCID 67355773 | — |
Reaction Steps
3-(3-Cyano-1H-indol-6-yl)-3-phenyl-acrylic acid ethyl ester CLII was prepared from 6-bromo-1H-indole-3-carbonitrile using the procedure described above for preparation of 3-(6-Methoxy-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester CXVI (Example 25).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446118B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-f2333a114fa8483ebcb9ef84295fbfc0 |
| Source note | uspto-grants-2008_11 |