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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268836Generated: November 2, 2026

3-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamide → 3-(3-Cyano-1H-indol-6-yl)-3-phenyl-propionic acid ethyl ester

https://huagongshe.com/reaction/268836

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamideHCID 59831745—
Reactant3-(3-Cyano-1H-indol-6-yl)-3-phenyl-acrylic acid ethyl esterHCID 67355773—
Product3-(3-Cyano-1H-indol-6-yl)-3-phenyl-propionic acid ethyl esterHCID 67356688—

Reaction Steps

3-(3-Cyano-1H-indol-6-yl)-3-phenyl-propionic acid ethyl ester CLIII was prepared from 3-(3-cyano-1H-indol-6-yl)-3-phenyl-acrylic acid ethyl ester using the procedure described above for preparation of 3-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamide XIX (Example 4).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446118B2
Source datasetuspto-grants-2008_11
ORD IDord-cf21a18bb30d4740ae2eec0a627246e0
Source noteuspto-grants-2008_11