HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(pyridin-2-yl)acrylate → 3-(1H-Indol-6-yl)-3-pyridin-2-yl-acrylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(pyridin-2-yl)acrylate | HCID 370265 | — |
| Reactant | 6-Bromoindole | HCID 676493 | — |
| Reactant | 3-(3-cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester | HCID 67355322 | — |
| Product | 3-(1H-Indol-6-yl)-3-pyridin-2-yl-acrylic acid ethyl ester | HCID 67355706 | — |
Reaction Steps
3-(1H-Indol-6-yl)-3-pyridin-2-yl-acrylic acid ethyl ester CLVII was prepared from 6-bromo-1H-indole and 3-pyridin-2-yl-acrylic acid ethyl ester using the procedure described for preparation of 3-(3-Cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester LVIII (Example 14).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446118B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-4561b63572c447fdbeee4ab93926d7ba |
| Source note | uspto-grants-2008_11 |