4-Bromo-7-methoxy-1H-indazole → HCID 67355113, compound

HRID 268860Notes

Reaction equation

HRID 268860 reaction equation
Br[C:2]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]2[C:3]=1[CH:4]=[N:5][NH:6]2.[CH2:13]([O:15][C:16](=[O:36])[CH:17]=[C:18](C1C=CC=C2C=1C(C#N)=CN2)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[CH3:14]>>[CH2:13]([O:15][C:16](=[O:36])[CH:17]=[C:18]([C:2]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]2[C:3]=1[CH:4]=[N:5][NH:6]2)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[CH3:14]

Participants

3

Reactant 2

HCID 598317114-Bromo-7-methoxy-1H-indazoleHCID 673553223-(3-cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester

Product 1

HCID 67355113HCID 67355113, compound

Procedure

Compound CXCVII was prepared from 4-Bromo-7-methoxy-1H-indazole using the procedure described for preparation of 3-(3-Cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester LVIII (Example 14).

Sources & evidence

ORD record
ord-c8f013880f224d7aa63fa6b7d473f252
Source dataset
uspto-grants-2008_11
Patent number
US07446118B2

Reaction notes

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