5-Bromo-3-methoxy-indazole-1-carboxylic acid ethyl ester → 5-bromo-3-methoxy-1H-indazole
Reaction equation
C(OC([N:6]1[C:14]2[C:9](=[CH:10][C:11]([Br:15])=[CH:12][CH:13]=2)[C:8]([O:16][CH3:17])=[N:7]1)=O)C.BrC1C=CC=C2C=1C(OC)=NN2>>[Br:15][C:11]1[CH:10]=[C:9]2[C:14](=[CH:13][CH:12]=1)[NH:6][N:7]=[C:8]2[O:16][CH3:17]Participants
3
Procedure
5-Bromo-3-methoxy-1H-indazole CCX was prepared from 5-Bromo-3-methoxy-indazole-1-carboxylic acid ethyl ester using the procedure described for preparation of 4-Bromo-3-methoxy-1H-indazole CLXXXVI (Example 37).
Sources & evidence
- ORD record
- ord-3859f346112d4f72bb1de559af693837
- Source dataset
- uspto-grants-2008_11
- Patent number
- US07446118B2
Reaction notes
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