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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268867Generated: November 2, 2026

3-(3-methoxy-1H-indazol-5-yl)-3-phenyl-acrylic acid ethyl ester → 3-(3-Methoxy-1H-indazol-5-yl)-N-methyl 3-phenyl-acrylamide

https://huagongshe.com/reaction/268867

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-methoxy-1H-indazol-5-yl)-3-phenyl-acrylic acid ethyl esterHCID 67355147—
Reactant3-(3-cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl esterHCID 67355322—
Product3-(3-Methoxy-1H-indazol-5-yl)-N-methyl 3-phenyl-acrylamideHCID 67356679—

Reaction Steps

The amide compound CCXII was prepared from 3-(3-methoxy-1H-indazol-5-yl)-3-phenyl-acrylic acid ethyl ester using the procedure described for preparation of 3-(1H-Indol-7-yl)-N-methyl-3-phenyl-acrylamide XVIII (see Example 4).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446118B2
Source datasetuspto-grants-2008_11
ORD IDord-afc12eb6408e418c978758a6c9a3bc07
Source noteuspto-grants-2008_11