3-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamide → HCID 59831789, compound

HRID 268891Notes

Reaction equation

HRID 268891 reaction equation
[CH3:1][O:2][C:3]1[C:11]2[C:6](=[CH:7][C:8]([C:12]([C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([CH3:24])[N:19]=3)=[CH:13][C:14]([NH:16][CH3:17])=[O:15])=[CH:9][CH:10]=2)[NH:5][N:4]=1.N1C2C(=CC=CC=2C(C2C=CC=CC=2)CC(NC)=O)C=C1>>[CH3:1][O:2][C:3]1[C:11]2[C:6](=[CH:7][C:8]([CH:12]([C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([CH3:24])[N:19]=3)[CH2:13][C:14]([NH:16][CH3:17])=[O:15])=[CH:9][CH:10]=2)[NH:5][N:4]=1

Participants

3

Reactant 2

HCID 598317453-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamideHCID 67356004HCID 67356004, compound

Product 1

HCID 59831789HCID 59831789, compound

Procedure

3-(3-Methoxy-1H-indazol-6-yl)-N-methyl-3-(6-methyl-pyridin-2yl)-propionamide CCXLV was prepared from 3-(3-methoxy-1H-indazol-6-yl)-N-methyl-3-(6-methyl-pyridin-2yl)-acrylamide using the procedure described for preparation of 3-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamide XIX (Example 4).

Sources & evidence

ORD record
ord-f4add954fb824d41846f824040b17e19
Source dataset
uspto-grants-2008_11
Patent number
US07446118B2

Reaction notes

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