HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-2-methyl-1,3-propanediol → 3-Bromo-N-(2-hydroxy-1-hydroxymethyl-1-methyl-ethyl)-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-2-methyl-1,3-propanediol | HCID 1531 | — |
| Reactant | m-Bromobenzenesulphonyl chloride | HCID 17943 | — |
| Product | 3-Bromo-N-(2-hydroxy-1-hydroxymethyl-1-methyl-ethyl)-benzenesulfonamide | HCID 67000702 | 56.1% |
Reaction Steps
Prepared by general procedure III from 2-amino-2-methyl-1,3-propanediol (2.71 g, 25 mmol) and commercially available 3-bromobenzenesulfonyl chloride (0.72 mL, 5 mmol) to give the title compound as a white solid (0.91 g, 12%). MS (ISN) 322.1 [(M−H)−], 324.1 [(M+2−H)−].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446113B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-9ae0effa9a344084bd9fa4e6cb266664 |
| Source note | uspto-grants-2008_11 |