3-Aminopropionitrile → HCID 8403806, compound

HRID 268944Notes

Reaction equation

HRID 268944 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([S:8](Cl)(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1.[NH2:12][CH2:13][CH2:14][C:15]#[N:16]>>[Br:1][C:2]1[CH:3]=[C:4]([S:8]([NH:16][CH2:15][CH2:14][C:13]#[N:12])(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 16473-AminopropionitrileHCID 17943m-Bromobenzenesulphonyl chloride

Product 1

HCID 8403806HCID 8403806, compoundYield 55.9%

Procedure

Prepared by general procedure III from 3-Bromobenzenesulfonyl chloride (10.0 g, 38 mmol) and 3-aminopropanonitrile (2.96 g, 42 mmol) to give the title compound (6.14 g, 55%) of an off-white solid. MS (ISP) 308.1 [(M+NH4)+].

Sources & evidence

ORD record
ord-e74e4cd8ad294497a28e017b4289ff9e
Source dataset
uspto-grants-2008_11
Patent number
US07446113B2

Reaction notes

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