p-Bromobenzenesulfonyl chloride → 4-[(4-Bromobenzene)sulfonyl]morpholine

HRID 268949Notes

Reaction equation

HRID 268949 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](Cl)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[NH:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)(=[O:10])=[O:9])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7396p-Bromobenzenesulfonyl chlorideHCID 8083Morpholine

Product 1

HCID 2531284-[(4-Bromobenzene)sulfonyl]morpholineYield 98%

Procedure

Prepared by general procedure III from 4-bromobenzenesulfonyl chloride (5.0 g, 20 mmol) and morpholine (1.88 g, 22 mmol) to give the title compound (5.90 g, 98%) as a white crystalline solid. MS (ISP) 306.1[(M+H)+].

Sources & evidence

ORD record
ord-61b7337f98bc4c9783f9f93e498d7d17
Source dataset
uspto-grants-2008_11
Patent number
US07446113B2

Reaction notes

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