Ethanolamine → 4-Bromo-N-(2-hydroxyethyl)benzene-1-sulfonamide

HRID 268951Notes

Reaction equation

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](Cl)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[CH2:12]([CH2:14][NH2:15])[OH:13]>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:15][CH2:14][CH2:12][OH:13])(=[O:10])=[O:9])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 700Ethanolamine

HCID 7396p-Bromobenzenesulfonyl chloride

Product 1

HCID 4585694-Bromo-N-(2-hydroxyethyl)benzene-1-sulfonamideYield 98%

Procedure

Prepared by general procedure III from 4-bromobenzenesulfonyl chloride (5.0 g, 20 mmol) and ethanolamine (1.32 g, 22 mmol) to give the title compound (5.4 g, 98%) as an off-white solid. MS (ISP) 280.0[(M+H)+].

Sources & evidence

ORD record: ord-da020de796e04b76ace07af57f94c903
Source dataset: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07446113B2

Reaction notes

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