HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → N-(2-Dimethylaminoethyl)-N'-[2-(2-benzimidazolylmethylamino)-ethyl]thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | 2-Chloromethylbenzimidazole | HCID 78571 | — |
| Reactant | (2-Isothiocyanatoethyl)dimethylamine | HCID 3853726 | — |
| Reactant | N1-((1H-Benzo[d]imidazol-2-yl)methyl)ethane-1,2-diamine | HCID 15365342 | — |
| Product | N-(2-Dimethylaminoethyl)-N'-[2-(2-benzimidazolylmethylamino)-ethyl]thiourea | HCID 54373380 | — |
Reaction Steps
N-(2-Benzimidazolylmethyl)ethylenediamine, prepared by reacting ethylenediamine with 2-chloromethylbenzimidazole by the procedure of Example 40, is reacted with 2-dimethylaminoethyl isothiocyanate by the procedure of Example 40 to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04151288 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-54c3feb3870144ec9e983524851de7e2 |
| Source note | uspto-grants-1979_04 |