Ethanolamine → HCID 23537282, compound

HRID 268964Notes

Reaction equation

HRID 268964 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5](F)=[N:6][CH:7]=1.[CH2:9]([CH2:11][NH2:12])[OH:10]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([NH:12][CH2:11][CH2:9][OH:10])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 700EthanolamineHCID 27831685-Bromo-2-fluoropyridine

Product 1

HCID 23537282HCID 23537282, compoundYield 13.2%

Procedure

Prepared from 5-bromo-2-fluoropyridine (2.5 g, 14 mmol) and ethanolamine (4.34 g, 70 mmol) as described in example B.45. Obtained as a colorless oil (400 mg, 13%). MS (ISP) 217.2 [(M+H)+], 219.1 [(M+2+H)+].

Sources & evidence

ORD record
ord-0a31013ac4d44419981ebf9ba7a6e539
Source dataset
uspto-grants-2008_11
Patent number
US07446113B2

Reaction notes

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