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4-Chlorophenylboronic acid → 6-(4-Chloro-phenyl)-8-methyl-imidazo[1,2-a]pyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Chlorophenylboronic acid | HCID 74299 | — |
| 反応物 | 6-Bromo-8-methylimidazo(1,2-a)pyridine | HCID 5260647 | — |
| 生成物 | 6-(4-Chloro-phenyl)-8-methyl-imidazo[1,2-a]pyridine | HCID 67000262 | 75.2% |
反応手順
Prepared from 6-bromo-8-methyl-imidazo[1,2-a]pyridine (example C.20 step 1) (7.0 g, 33 mmol) and commercially available 4-chlorophenylboronic acid (6.005 g, 36 mmol) as described in example C.20 step 2. Obtained the title compound as a white solid (6.02 g, 75%). MS (ISP) 243.2 [(M+H)+], 245.1 [(M+2+H)+].
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07446113B2 |
| 出典データセット | uspto-grants-2008_11 |
| ORD ID | ord-208b8a88498d487b8428689e1d870cfe |
| 出典メモ | uspto-grants-2008_11 |