Ethane, 2-bromo-1,1-diethoxy- → 6-Bromoimidazo[1,2-a]pyridine-8-carbonitrile

Beteiligte Stoffe

Reaktionsschritte

Prepared from 2-amino-5-bromo-nicotinonitrile (example C.23 step 1) (26 g, 131 mmol) and bromoacetaldehyde diethyl acetal (90%, 45 mL, 263 mmol) as described in example C.20 step 1. Obtained the title compound as a light brown solid (9.3 g, 32%).MS (ISP) 222.1 [(M+H)+], 224 [(M+2+H)+].

Herkunft & Nachweise