HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 3-Bromo-5-(4-chlorophenyl)pyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 5-(4-Chlorophenyl)pyridin-2-amine | HCID 13242644 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 3-Bromo-5-(4-chlorophenyl)pyridin-2-amine | HCID 58067823 | — |
Reaction Steps
Prepared from crude 5-(4-chloro-phenyl)-pyridin-2-ylamine (example C.27 step 1) (ca. 50 mmol) in acetonitrile (100 mL) and NBS (9.34 g, 53 mmol) as described in example C.25 step 2. Obtained the crude 3-bromo-5-(4-chloro-phenyl)-pyridin-2-ylamine a dark brown solid (76% pure).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446113B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-dd26972c0bbf40f6a8f29a1bf111c12a |
| Source note | uspto-grants-2008_11 |