HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine chloride → 8-Fluoro-3-iodo-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine chloride | HCID 24640 | — |
| Reactant | 8-Fluoro-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine | HCID 67000119 | — |
| Product | 8-Fluoro-3-iodo-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine | HCID 67001206 | 78% |
Reaction Steps
Prepared from 8-fluoro-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine (example C.29 step 5) (1.95 g, 7.9 mmol) and iodine monochloride as described in example C.20 step 3. Obtained the title compound as a light brown solid (1.8 g, 78%). MS (ISP) 407.0 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446113B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-0556e5a554a345c6a64615bf54ea6dd1 |
| Source note | uspto-grants-2008_11 |