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HRID269171

反应详情

EQUATION

反应方程式

HRID 269171 的结构方程式

REACTANTS

反应物

2
结构：NS(=O)(=O)c1cc(Br)c(F)cc1F
HCID2773295

5-bromo-2,4-difluorobenzenesulfonamide

C6H4BrF2NO2S

结构：C#Cc1cnn2c(C(F)(F)F)cc(-c3ccc(Cl)cc3)nc12
HCID86607995

未命名化合物

PRODUCTS

生成物

1
结构：NS(=O)(=O)c1cc(C#Cc2cnn3c(C(F)(F)F)cc(-c4ccc(Cl)cc4)nc23)c(F)cc1F
HCID11852721

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 5-(4-chloro-phenyl)-3-ethynyl-7-trifluoromethyl pyrazolo[1,5-a]pyrimidine (example C.4) (161 mg, 0.5 mmol) and 5-bromo-2,4-difluoro-benzenesulfonamide (136 mg, 0.5 mmol) according to general procedure II. Obtained as a yellow solid (146 mg, 57%). MS (ISP) 513.3 [(M+H)+]; mp 292-293° C.