Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diazomethane → 3-(2',4'-Difluoro-4-biphenylyl)-2-butenoic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diazomethane | HCID 9550 | — |
| 반응물 | 3-(2',4'-Difluoro-4-biphenylyl)-2-butenoic acid | HCID 54010068 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-(2',4'-Difluoro-4-biphenylyl)-2-butenoic acid methyl ester | HCID 53696332 | — |
반응 단계
1 g. of 3-(2',4'-difluoro-4-biphenylyl)-2-butenoic acid is dissolved in 10 ml. of THF and an ethereal solution of diazomethane is added dropwise, with stirring, until no further evolution of nitrogen is observed. After 20 minutes, the mixture is evaporated to give 3-(2',4'-difluoro-4-biphenylyl)-2-butenoic acid methyl ester, m.p. 90°-92°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04151302 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-c6770c4a66034c95bef89287f848c826 |
| 출처 메모 | uspto-grants-1979_04 |