HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-fluoropyridine → HCID 86608076, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-fluoropyridine | HCID 2783168 | — |
| Reactant | 3-Ethynyl-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine | HCID 71539732 | — |
| Product | HCID 86608076 | HCID 86608076 | — |
Reaction Steps
The title compound was prepared from 3-ethynyl-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine (example C.1) (355 mg, 1.0 mmol) and commercially available 5-bromo-2-fluoropyridine (237 mg, 1.0 mmol) according to general procedure II. Obtained as an orange solid (470 mg, 69%). MS (ISP) 451.1 [(M+H)+]; mp 213-216° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446113B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-a80bcaedf19c4e4fa1ab3b6748dcba89 |
| Source note | uspto-grants-2008_11 |