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HRID269242

反应详情

EQUATION

反应方程式

HRID 269242 的结构方程式

REACTANTS

反应物

2
结构：NS(=O)(=O)c1cc(Br)c(F)cc1F
HCID2773295

5-bromo-2,4-difluorobenzenesulfonamide

C6H4BrF2NO2S

结构：C#Cc1cnc2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)cn12
HCID86608011

3-Ethynyl-8-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine

C17H8F6N2

PRODUCTS

生成物

1
结构：NS(=O)(=O)c1cc(C#Cc2cnc3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)cn23)c(F)cc1F
HCID16735751

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 3-ethynyl-8-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine (example C.18) (310 mg, 0.88 mmol) and 5-Bromo-2,4,-difluorobenzenesulfonamide (226 mg, 0.83 mmol) according to general procedure II. Obtained as an off-white solid (56 mg, 12%). MS (ISP) 546.2 [(M+H)+]; mp 306-307° C.