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HRID269275

反应详情

EQUATION

反应方程式

HRID 269275 的结构方程式

REACTANTS

反应物

2
结构：NS(=O)(=O)c1ccc(Br)s1
HCID1241304

5-Bromothiophene-2-sulfonamide

C4H4BrNO2S2

结构：C#Cc1cnc2c(C#N)cc(-c3ccc(C(F)(F)F)cc3)cn12
HCID86608096

未命名化合物

PRODUCTS

生成物

1
结构：N#Cc1cc(-c2ccc(C(F)(F)F)cc2)cn2c(C#Cc3ccc(S(N)(=O)=O)s3)cnc12
HCID16738466

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 3-ethynyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine-8-carbonitrile (example C.23) (150 mg, 0.5 mmol) and commercially available 5-bromothiophene-2-sulfonamide (117 mg, 0.5 mmol) according to general procedure II. Obtained as an off-white solid (80 mg, 35%). MS (ISP) 473.1 [(M+H)+]; mp 267-269° C.