Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 269366Generated: October 28, 2026

2-Amino-5-bromopyridine → HCID 67000927, compound

https://huagongshe.com/reaction/269366

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-bromopyridineHCID 70622—
Reactant5-(4-Chloro-phenyl)-3-ethynyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidineHCID 86607995—
ProductHCID 67000927HCID 67000927—

Reaction Steps

The title compound was prepared from 5-(4-chloro-phenyl)-3-ethynyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine (example C.4) (322 mg, 1.0 mmol) and 2-amino-5-bromopyridine (173 mg, 1.0 mmol) according to general procedure II. Obtained as an orange solid (71 mg, 17%). MS (ISP) 414.3 [(M+H)+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446113B2
Source datasetuspto-grants-2008_11
ORD IDord-60f7bbed31544ec5bb9c42bb1c739c41
Source noteuspto-grants-2008_11