反应详情

A mixture of 1 g of 1-phosphono-2-(2-pyridinyl)ethanesulfonic acid and 0.5 g of palladium on charcoal catalyst in 50 ml of distilled water is hydrogenated on a Parr apparatus at 40 PSI for about 2 days. The catalyst is removed by filtration, and the filtrate is concentrated to a few mls. Ethanol is added slowly to precipitate a solid, which is recrystallized from water/ethanol to afford 1-phosphono-2-(2-piperidinyl)ethanesulfonic acid.

1. customThe catalyst is removed by filtration
2. concentrationthe filtrate is concentrated to a few mls
3. additionEthanol is added slowly
4. customto precipitate a solid, which
5. customis recrystallized from water/ethanol