Hydrochloric Acid → HCID 178428844, compound

Participants

Reaction Steps

546 mg of guanidinium chloride and 535 mg of KOtBu were stirred in 20 ml of anhydrous DMF at RT for 30 minutes. Then 500 mg of methyl 5-methanesulfonyl-4-(4-methanesulfonyl-3-pentafluorosulfanylphenoxy)-2-methylbenzoate were added, and the mixture was left to stand at RT for 16 h. The reaction mixture was poured into 20 ml of water, adjusted to pH=8 with aqueous HCl solution and extracted 3 times with 50 ml of EA each time. The combined EA phases were then washed with 20 ml of a 5% aqueous NaHCO3 solution and dried over MgSO4, and the solvent was removed in vacuo. 420 mg of an amorphous solid were obtained.

Provenance & Evidence