Trifluoroacetic acid → HCID 59832236, compound

Participants

Reaction Steps

A solution of the above carbamic acid tert-butyl ester (306 mg, 0.54 mmol) was dissolved in CH2Cl2 (1 ml), treated with TFA (3 ml) for 1 hour. The reaction was evaporated and the solid residue triturated with ether and hexane, and filtered to give the final desired product as a white solid (402 mg) in 80% overall yield. FIA-MS m/e=458.2 (M+H), 456.3 (M−H).

Provenance & Evidence