5-Bromo-2-fluoropyridine → HCID 178505652, compound

HRID 269520Notes

Reaction equation

HRID 269520 reaction equation
[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[CH:10]=[N:11][O:12][C:13]=1[C:14]1[C:22]2[C:17](=[N:18][CH:19]=[CH:20][CH:21]=2)[NH:16][N:15]=1.[Br:23]C1C=CC(F)=NC=1>>[Br:23][C:20]1[CH:21]=[C:22]2[C:14]([C:13]3[O:12][N:11]=[CH:10][C:9]=3[C:3]3[CH:4]=[CH:5][CH:6]=[C:7]([F:8])[C:2]=3[F:1])=[N:15][NH:16][C:17]2=[N:18][CH:19]=1

Participants

3

Reactant 2

HCID 27831685-Bromo-2-fluoropyridineHCID 178505653HCID 178505653, compound

Product 1

HCID 178505652HCID 178505652, compound

Procedure

5-Bromo-3-(4-(2,3-difluorophenyl)isoxazol-5-yl)-1H-pyrazolo[3,4-b]pyridine was prepared according to the method described for the preparation of 3-(4-(2,3-difluorophenyl)isoxazol-5-yl)-1H-pyrazolo[3,4-b]pyridine starting with 5-bromo-2-fluoropyridine.

Sources & evidence

ORD record
ord-6a35027cc8104e498790c8bb279f0562
Source dataset
uspto-grants-2008_11
Patent number
US07446199B2

Reaction notes

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