HuagongsheHuagongshe Chemistry Print Report · For research reference only
2'-Benzyloxy-biphenyl-2-boronic acid → Ethyl 4-methyl-2''-[(phenylmethyl)oxy]-1,1':2',1''-terphenyl-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2'-Benzyloxy-biphenyl-2-boronic acid | HCID 58730990 | — |
| Reactant | Ethyl 4-(acetylamino)-2''-[(phenylmethyl)oxy]-5''-(trifluoromethyl)-1,1':2',1''-terphenyl-2-carboxylate | HCID 58731007 | — |
| Reactant | Ethyl 2'-bromo-4-methyl-2-biphenylcarboxylate | HCID 69309503 | — |
| Product | Ethyl 4-methyl-2''-[(phenylmethyl)oxy]-1,1':2',1''-terphenyl-2-carboxylate | HCID 58730980 | — |
Reaction Steps
Prepared in a similar way to ethyl 4-(acetylamino)-2″-[(phenylmethyl)oxy]-5″-(trifluoromethyl)-1,1′:2′,1″-terphenyl-2-carboxylate but using {2′-[(phenylmethyl)oxy]-2-biphenylyl}boronic acid instead of [2-[(phenylmethyl)oxy]-5-(trifluoromethyl)phenyl]boronic acid and ethyl 2′-bromo-4-methyl-2-biphenylcarboxylate instead of ethyl 4-(acetylamino)-2′-bromo-2-biphenylcarboxylate. LC/MS t=4.11, [MH+] 423.1
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446222B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-129eee260339493b8790589d99367e09 |
| Source note | uspto-grants-2008_11 |