HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dichloroethane → HCID 131727147, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | Z-Ndelta-Boc-L-ornithine | HCID 7350734 | — |
| Reactant | tert-butyl N-(3-amino-2-hydroxypropyl)carbamate | HCID 10511887 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 131727147 | HCID 131727147 | — |
Reaction Steps
Preparation takes place in analogy to Example 79A from 300 mg (0.82 mmol) of N2-[(benzyloxy)carbonyl]-N5-(tert-butoxycarbonyl)-L-ornithine and 202 mg (1.06 mmol) of tert-butyl(3-amino-2-hydroxypropyl)carbamate in 6 ml of dimethylformamide with the addition of 204 mg (1.06 mmol) of EDC and 33 mg (0.25 mmol) of HOBt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446102B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-287500946745438cb232d3f2a03e0e04 |
| Source note | uspto-grants-2008_11 |