HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boc-Dab(Z)-Ol (S) → tert-butyl[(1S)-3-amino-1-(hydroxymethyl)propyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boc-Dab(Z)-Ol (S) | HCID 59722512 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | tert-butyl[(1S)-3-amino-1-(hydroxymethyl)propyl]carbamate | HCID 59722466 | — |
Reaction Steps
Preparation takes place in analogy to Example 81A from 237 mg (0.7 mmol) of benzyl{(3S)-3-[(tert-butoxycarbonyl)amino]-4-hydroxybutyl}carbamate (Example 236A) in 50 ml of ethanol with the addition of 23 mg of palladium on activated carbon (10%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446102B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-7f6db31506e64e069390104b920f53f4 |
| Source note | uspto-grants-2008_11 |