HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nalpha-Boc-Ndelta-Cbz-ornithinol → tert-butyl[(1S)-4-amino-1-(hydroxymethyl)butyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nalpha-Boc-Ndelta-Cbz-ornithinol | HCID 11772551 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | tert-butyl[(1S)-4-amino-1-(hydroxymethyl)butyl]carbamate | HCID 88986916 | — |
Reaction Steps
Preparation takes place in analogy to Example 81A from 0.232 g (0.66 mmol) of benzyl{(4S)-4-[(tert-butoxycarbonyl)amino]-5-hydroxypentyl}carbamate (Example 246A) in 50 ml of ethanol with the addition of 23 mg of palladium on activated carbon (10%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446102B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-f93464bae592471ca7a7e4587f1faab5 |
| Source note | uspto-grants-2008_11 |