6-Amino-1-hexanol → Methyl 3-(sec-butylcarbamoyl)-2-(6-hydroxyhexylamino)propanoate

HRID 269714Notes

Reaction equation

HRID 269714 reaction equation
[CH:1]([NH:5][C:6]([CH:8]=[CH:9][C:10]([O:12][CH3:13])=[O:11])=[O:7])([CH2:3][CH3:4])[CH3:2].[NH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][OH:21]>>[CH:1]([NH:5][C:6]([CH2:8][CH:9]([NH:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][OH:21])[C:10]([O:12][CH3:13])=[O:11])=[O:7])([CH2:3][CH3:4])[CH3:2]

Participants

3

Reactant 2

HCID 199606-Amino-1-hexanolHCID 54128810Methyl 3-(sec-butylcarbamoyl)acrylate

Product 1

HCID 21079858Methyl 3-(sec-butylcarbamoyl)-2-(6-hydroxyhexylamino)propanoate

Procedure

To methyl 3-(sec-butylcarbamoyl)acrylate from the above reaction at room temperature was added the 6-amino-1-hexanol (13.7 g, 117 mmol) and the resulting mixture was stirred overnight to give the desired product.

Sources & evidence

ORD record
ord-d5d996c7990543338c22ce8bfb2d9741
Source dataset
uspto-grants-2008_11
Patent number
US07449242B2

Reaction notes

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