Dimethyl Sulfoxide → HCID 59833360, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 5-fluoro-2-[(5-fluoropyridin-2-yl)-carbonylamino]-N-(5-chloropyridin-2-yl)benzamide (502 mg, 1.29 mmol), DMSO (4 mL) and sodium thiomethoxide (95 mg, 1.36 mmoL) was heated to 50° C. for 18 h. The reaction was cooled, added water, filtered, and dried. The solid was triturated with CH2Cl2 and filtered to give the title compound as a white solid (461 mg, 86%).

Provenance & Evidence