4-Methoxy-7-morpholinobenzo[d]thiazol-2-amine → HCID 11690229, compound

HRID 269742Notes

Reaction equation

HRID 269742 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH2:12])[S:11][C:7]=2[C:6]([N:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[CH:5][CH:4]=1.[C:19]12([CH:26]([CH3:30])[C:27](Cl)=[O:28])[O:25][CH:22]([CH2:23][CH2:24]1)[CH2:21][CH2:20]2>>[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:27](=[O:28])[CH:26]([C:19]34[O:25][CH:22]([CH2:23][CH2:24]3)[CH2:21][CH2:20]4)[CH3:30])[S:11][C:7]=2[C:6]([N:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 114028614-Methoxy-7-morpholinobenzo[d]thiazol-2-amineHCID 87779849HCID 87779849, compound

Product 1

HCID 11690229HCID 11690229, compound

Procedure

Using 4-methoxy-7-morpholin-4-yl-benzothiazol-2-ylamine and 2-(7-oxa-bicyclo[2.2.1]hept-1-yl)-propionyl chloride, the title compound was obtained as white solid (67% yield). MS: m/e=418(M+H+), mp 195-197° C.

Sources & evidence

ORD record
ord-1aa4734c33e6403595ffc53bc9d658ec
Source dataset
uspto-grants-2008_11
Patent number
US07449461B2

Reaction notes

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