HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → HCID 69181070, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 2,4(1H,3H)-Pyrimidinedione, nitro- | HCID 151358 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 69181070 | HCID 69181070 | — |
Reaction Steps
As shown in Scheme 1, a suitable nitro-uracil precursor, (1), is mixed with an appropriate aldehyde, (2), and piperidine, in a suitable solvent such as ethanol. The solution is heated to reflux for approximately 10-20 hours. After reflux, the mixture is concentrated and purified using conventional methods, such as thin layer chromatography, to produce the vinyl-nitro-uracil (3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449473B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-8c6aeed16de9417a8f4b15f68c80124a |
| Source note | uspto-grants-2008_11 |