HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzoyl-4-(4-methoxyphenyl)piperazine → 1-Benzoyl-4-(4-hydroxyphenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzoyl-4-(4-methoxyphenyl)piperazine | HCID 2664331 | — |
| Reactant | 1-(4-Methoxyphenyl)-4-phenethylpiperazine | HCID 15527076 | — |
| Product | 1-Benzoyl-4-(4-hydroxyphenyl)piperazine | HCID 4086203 | 76.7% |
Reaction Steps
Production Example 2 was repeated except that 1-(4-methoxyphenyl)-4-phenethylpiperazine was replaced with 1-benzoyl-4-(4-methoxyphenyl)piperazine (193 mg), and the resulting crude product was purified on TLC (developer, chloroform: acetone=4:1) to provide 1-benzoyl-4-(4-hydroxyphenyl)piperazine (141 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449466B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-eff20b8044ec47d8907dbb69c9bd52ff |
| Source note | uspto-grants-2008_11 |