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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 269875Generated: November 1, 2026

HCID 23111467, compound → HCID 23111427, compound

https://huagongshe.com/reaction/269875

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 23111467HCID 23111467—
Reactant1-(4-Methoxy-3-methylphenyl)-4-phenethylpiperazineHCID 23111510—
ProductHCID 23111427HCID 2311142752.2%

Reaction Steps

Production Example 10 was repeated except that 1-(4-methoxy-3-methylphenyl)-4-phenethylpiperazine was replaced with 5-methoxy-2-[4-(3-phenylpropyl)piperidino]benzonitrile (290 mg), and the resulting crude product was purified on TLC (developer, hexane: ethyl acetate=3:1) to provide 5-hydroxy-2-[4-(3-phenyl-propyl)piperidino]benzonitrile (145 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07449466B2
Source datasetuspto-grants-2008_11
ORD IDord-5ae9c3f8fc6a496c86a3db8dbf577685
Source noteuspto-grants-2008_11