Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(4-Benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine → 4-[4-(3-Cyclo-pentylpropyl)piperazin-1-yl]-2-fluorophenol hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(4-Benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine | HCID 23111408 | — |
| 반응물 | 1-(4-Benzyloxy-3-fluorophenyl)-4-(3-cyclopentylpropyl)piperazine | HCID 23111413 | — |
| 생성물 | 4-[4-(3-Cyclo-pentylpropyl)piperazin-1-yl]-2-fluorophenol hydrochloride | HCID 23111453 | — |
반응 단계
Production Example 30 was repeated except that 1-(4-benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine was replaced with 1-(4-benzyloxy-3-fluorophenyl)-4-(3-cyclopentylpropyl)-piperazine (494 mg), to provide 4-[4-(3-cyclo-pentylpropyl)piperazin-1-yl]-2-fluorophenol hydrochloride (398 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07449466B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-63c34ff4ba224e64bbb6bf7a39c8b536 |
| 출처 메모 | uspto-grants-2008_11 |