HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine → 4-[4-(3-Cyclohexylpropyl)piperazin-1-yl]-2-fluorophenol hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine | HCID 23111408 | — |
| Reactant | 1-(4-Benzyloxy-3-fluorophenyl)-4-(3-cyclohexylpropyl)piperazine | HCID 23111415 | — |
| Product | 4-[4-(3-Cyclohexylpropyl)piperazin-1-yl]-2-fluorophenol hydrochloride | HCID 23111414 | — |
Reaction Steps
Production Example 30 was repeated except that 1-(4-benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine was replaced with 1-(4-benzyloxy-3-fluorophenyl)-4-(3-cyclohexylpropyl)-piperazine (1.45 g), to provide 4-[4-(3-cyclohexylpropyl)piperazin-1-yl]-2-fluorophenol hydrochloride (1.17 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449466B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-a36d1ae40d554b45837fe84781e50f3f |
| Source note | uspto-grants-2008_11 |