反应详情

Production Example 2 was repeated except that 1-(4-methoxyphenyl)-4-phenethylpiperazine was replaced with 4-(4-benzyloxy-3-fluorophenyl)-1-valerylpiperazine (367 mg). The resulting crude product was purified on TLC (developer, chloroform: methanol=12:1) to provide 4-(3-fluoro-4-hydroxyphenyl)-1-valerylpiperazine (61 mg).

1. customThe resulting crude product was purified on TLC (developer, chloroform: methanol=12:1)