HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-chlorophenol → 2-Acetylamino-4-chlorophenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-chlorophenol | HCID 7265 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Acetylamino-4-chlorophenol | HCID 95258 | 80.8% |
Reaction Steps
To a suspension of 2-amino-4-chlorophenol (1.43 g, 10.0 mmol) in methanol was added acetic anhydride (0.945 mL, 10.0 mmol) and the reaction mixture was stirred at room temperature for 2 h. The volatiles were removed in vacuo to give the subtitled compound (1.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449475B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-40c22dff81724e1d9b69e1626f222a07 |
| Source note | uspto-grants-2008_11 |