Formaldehyde → Ethyl 2-(3-chlorophenyl)acrylate

HRID 270209Notes

Reaction equation

C=O.O=[C:4]([CH:10]([C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([Cl:22])[CH:17]=1)[C:11]([O:13][CH2:14][CH3:15])=[O:12])C(OCC)=O>>[Cl:22][C:18]1[CH:17]=[C:16]([C:10](=[CH2:4])[C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:21]=[CH:20][CH:19]=1

Participants

Reactant 2

HCID 712Formaldehyde

HCID 21964382Diethyl 2-oxo-3-(3-chlorophenyl)succinate

Product 1

HCID 21964393Ethyl 2-(3-chlorophenyl)acrylate

Procedure

The title compound is prepared according to the method of Klioze and Ehrgott (U.S. Pat. No. 4,216,218) from formaldehyde and diethyl 2-oxo-3-(3-chlorophenyl)succinate (Example 26, Part A).

Sources & evidence

ORD record: ord-98f9f5116bcb4792be4edea8ba6ef023
Source dataset: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07449490B2

Reaction notes

Loading…