1,3-Dibromobutane → 6-(4-Bromo-butoxy)-3-methyl-benzo[d]isothiazole

HRID 270257Notes

Reaction equation

HRID 270257 reaction equation
[CH3:1][C:2]1[C:6]2[CH:7]=[CH:8][C:9]([OH:11])=[CH:10][C:5]=2[S:4][N:3]=1.[Br:12][CH2:13][CH2:14][CH:15](Br)[CH3:16]>>[Br:12][CH2:13][CH2:14][CH2:15][CH2:16][O:11][C:9]1[CH:8]=[CH:7][C:6]2[C:2]([CH3:1])=[N:3][S:4][C:5]=2[CH:10]=1

Participants

3

Reactant 2

HCID 78891,3-DibromobutaneHCID 1357420033-Methylbenzo[d]isothiazol-6-ol

Product 1

HCID 223139206-(4-Bromo-butoxy)-3-methyl-benzo[d]isothiazole

Procedure

In analogy to example 2.1, 3-Methyl-benzo[d]isothiazol-6-ol and 1,3-dibromobutane were converted to yield 6-(4-Bromo-butoxy)-3-methyl-benzo[d]isothiazole as brown oil, MS: 300 (MH+, 1 Br).

Sources & evidence

ORD record
ord-dc4efebc80c5494c9054f67982ea0f33
Source dataset
uspto-grants-2008_11
Patent number
US07449483B2

Reaction notes

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