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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 270264Generated: October 30, 2026

1-Methylpiperazine → 3-(4-Bromo-phenyl)-6-[4-(4-methyl-piperazin-1-yl)-butoxy]-benzo[d]isothiazole

https://huagongshe.com/reaction/270264

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
ReactantHCID 22313931HCID 22313931—
Product3-(4-Bromo-phenyl)-6-[4-(4-methyl-piperazin-1-yl)-butoxy]-benzo[d]isothiazoleHCID 10204833—

Reaction Steps

In analogy to example 3.1, 6-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-benzo[d]isothiazole and 1-Methylpiperazine were converted to yield 3-(4-Bromo-phenyl)-6-[4-(4-methyl-piperazin-1-yl)-butoxy]-benzo[d]isothiazole as white solid, MS: 460(MH+, 1Br).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07449483B2
Source datasetuspto-grants-2008_11
ORD IDord-0618a8bd224f43279a5e58a9cbed3380
Source noteuspto-grants-2008_11