2-(Methylamino)ethanol → HCID 22313897, compound

HRID 270288Notes

Reaction equation

HRID 270288 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:22]=[CH:21][C:10]2[C:11]([C:14]3[CH:19]=[CH:18][C:17]([Br:20])=[CH:16][CH:15]=3)=[N:12][S:13][C:9]=2[CH:8]=1.[CH3:23][NH:24][CH2:25][CH2:26][OH:27]>>[Br:20][C:17]1[CH:18]=[CH:19][C:14]([C:11]2[C:10]3[CH:21]=[CH:22][C:7]([O:6][CH2:5][CH2:4][CH2:3][CH2:2][N:24]([CH3:23])[CH2:25][CH2:26][OH:27])=[CH:8][C:9]=3[S:13][N:12]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 80162-(Methylamino)ethanolHCID 22313931HCID 22313931, compound

Product 1

HCID 22313897HCID 22313897, compound

Procedure

According to the method in example 4, 6-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-benzo[d]isothiazole and 2-(methylamino)ethanol were converted to yield 2-[[4-[3-(4-Bromo-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl]-methyl-amino]-ethanol, MS: 436 (MH+, 1Br).

Sources & evidence

ORD record
ord-2aa96f72d0904fb398ec6f6d7ff8567d
Source dataset
uspto-grants-2008_11
Patent number
US07449483B2

Reaction notes

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